dihydrofolate reductase activity

Term ID

GO:0004146

Synonyms

• 5,6,7,8-tetrahydrofolate:NADP+ oxidoreductase activity
• 7,8-dihydrofolate reductase activity
• DHFR
• dihydrofolate reductase:thymidylate synthase activity
• dihydrofolate reduction
• dihydrofolic acid reductase activity
• dihydrofolic reductase activity
• folic acid reductase activity
• folic reductase activity
• NADPH-dihydrofolate reductase activity
• pteridine reductase:dihydrofolate reductase activity
• tetrahydrofolate dehydrogenase activity
• thymidylate synthetase-dihydrofolate reductase activity

Definition

Catalysis of the reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+. 1.5.1.3

References

• EC:1.5.1.3
• MetaCyc:DIHYDROFOLATEREDUCT-RXN
• RHEA:15009
• Reactome:R-HSA-1497794

Ontology

GO: Molecular Function    QuickGO    AmiGO