(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity

Term ID

GO:0003947

Synonyms

• asialo-GM2 synthase activity
• beta-1,4N-aetylgalactosaminyltransferase activity
• GalNAc-T activity
• ganglioside GM2 synthase activity
• ganglioside GM3 acetylgalactosaminyltransferase activity
• GM2 synthase activity
• GM2/GD2-synthase activity
• UDP acetylgalactosamine-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide acetylgalactosaminyltransferase activity
• UDP-N-acetyl-D-galactosamine:(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide N-acetyl-D-galactosaminyltransferase activity
• UDP-N-acetyl-D-galactosamine:1-O-[O-(N-acetyl-alpha-neuraminosyl)-(2->3)-O-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranosyl]-ceramide 1,4-beta-N-acetyl-D-galactosaminyltransferase activity
• UDP-N-acetylgalactosamine GM3 N-acetylgalactosaminyltransferase activity
• uridine diphosphoacetylgalactosamine-acetylneuraminylgalactosylglucosylceramide acetylgalactosaminyltransferase activity
• uridine diphosphoacetylgalactosamine-ganglioside GM3 acetylgalactosaminyltransferase activity
• uridine diphosphoacetylgalactosamine-hematoside acetylgalactosaminyltransferase activity

Definition

Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + (N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide = UDP + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide. 2.4.1.92

References

• EC:2.4.1.92
• MetaCyc:2.4.1.92-RXN
• RHEA:12588
• Reactome:R-HSA-8856223

Ontology

GO: Molecular Function    QuickGO    AmiGO