GTP cyclohydrolase II activity

Term ID

GO:0003935

Synonyms

• GTP 7,8-8,9-dihydrolase (diphosphate-forming)
• GTP-8-formylhydrolase activity
• guanosine triphosphate cyclohydrolase II

Definition

Catalysis of the reaction: GTP + 4 H2O = 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + formate + 3 H+ + 2 phosphate. 3.5.4.25

References

• EC:3.5.4.25
• KEGG_REACTION:R00425
• MetaCyc:GTP-CYCLOHYDRO-II-RXN
• RHEA:23704

Ontology

GO: Molecular Function    QuickGO    AmiGO