3-beta-hydroxy-delta5-steroid dehydrogenase (NAD+) activity

Term ID

GO:0003854

Synonyms

• 3-beta-hydroxy-5-ene steroid dehydrogenase activity
• 3-beta-hydroxy-D5-steroid dehydrogenase activity
• 3beta-HSDH
• 3beta-hydroxy steroid dehydrogenase/isomerase activity
• 3beta-hydroxy-5-ene steroid dehydrogenase activity
• 3beta-hydroxy-5-ene-steroid dehydrogenase activity
• 3beta-hydroxy-5-ene-steroid oxidoreductase activity
• 3beta-hydroxy-delta5-C27-steroid dehydrogenase/isomerase activity
• 3beta-hydroxy-delta5-C27-steroid oxidoreductase
• 3beta-hydroxy-delta5-steroid dehydrogenase activity
• 3beta-hydroxy-delta5-steroid:NAD+ 3-oxidoreductase activity
• 5-ene-3-beta-hydroxysteroid dehydrogenase activity
• delta5-3beta-hydroxysteroid dehydrogenase activity
• progesterone reductase activity
• steroid-delta5-3beta-ol dehydrogenase activity

Definition

Catalysis of the reaction: a 3-beta-hydroxy-delta(5)-steroid + NAD+ = a 3-oxo-delta(5)-steroid + NADH + H+. Also acts on on 3-beta-hydroxypregn-5-en-20-one to form progesterone. 1.1.1.145

References

• EC:1.1.1.145
• MetaCyc:1.1.1.145-RXN
• Reactome:R-HSA-192097
• Reactome:R-HSA-193789
• Reactome:R-HSA-193816
• Reactome:R-HSA-196350
• Reactome:R-HSA-196372

Ontology

GO: Molecular Function    QuickGO    AmiGO