Search Ontology:
GO: Biological Process

antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent

Term ID
GO:0002485
Synonyms
  • endogenous peptide antigen processing and presentation via MHC class I via ER pathway, TAP-dependent
  • TAP-dependent antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway
  • TAP-dependent endogenous peptide antigen processing and presentation via MHC class I via ER pathway
Definition
The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-dependent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following TAP-dependent transport from the cytosol. Class I here refers to classical class I molecules. (3)
References
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
is a type of
Phenotype
Phenotype caused by Genes