Search Ontology:
GO: Biological Process
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent
- Term ID
- GO:0002485
- Synonyms
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- endogenous peptide antigen processing and presentation via MHC class I via ER pathway, TAP-dependent
- TAP-dependent antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway
- TAP-dependent endogenous peptide antigen processing and presentation via MHC class I via ER pathway
- Definition
- The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-dependent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following TAP-dependent transport from the cytosol. Class I here refers to classical class I molecules. (3)
- References
- Ontology
- GO: Biological Process QuickGO AmiGO
- is a type of
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Phenotype
Phenotype caused by Genes