antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent

Term ID

GO:0002481

Synonyms

• exogenous peptide antigen processing and presentation via MHC class Ib, TAP-dependent
• TAP-dependent antigen processing and presentation of exogenous peptide antigen via MHC class Ib
• TAP-dependent exogenous peptide antigen processing and presentation via MHC class Ib

Definition

The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class Ib molecule. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family. 15928678

References

Ontology

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