antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent

Term ID

GO:0002480

Synonyms

• cross presentation
• cross-presentation
• exogenous peptide antigen processing and presentation via MHC class I, TAP-independent
• TAP-independent antigen processing and presentation of exogenous peptide antigen via MHC class I
• TAP-independent exogenous peptide antigen processing and presentation via MHC class I

Definition

The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class I here refers to classical class I molecules. (3)

References

• Reactome:R-HSA-1236977

Ontology

GO: Biological Process    QuickGO    AmiGO