Search Ontology:
GO: Biological Process
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
- Term ID
- GO:0002479
- Synonyms
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- cross presentation
- cross-presentation
- exogenous peptide antigen processing and presentation via MHC class I, TAP-dependent
- TAP-dependent antigen processing and presentation of exogenous peptide antigen via MHC class I
- TAP-dependent exogenous peptide antigen processing and presentation via MHC class I
- Definition
- The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class I molecule. Class I here refers to classical class I molecules. (3)
- References
- Ontology
- GO: Biological Process QuickGO AmiGO
- is a type of
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Phenotype
Phenotype caused by Genes