Search Ontology:
GO: Biological Process

immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor

Term ID
GO:0002415
Synonyms
  • antibody transcytosis mediated by pIgR
  • immunoglobulin transcytosis mediated by pIgR
Definition
The process of transporting polymeric IgA and polymeric IgM immunoglobulin, via transcytosis mediated by the polymeric immunoglobulin receptor (pIgR), from the basolateral surface to apical surface of an epithelial cell. At the apical surface the immunoglobulin binding portion of the pIgRis cleaved and remains bound to the transported immunoglobulin as secretory component (SC). The same process is used for the transport and excretion of IgA immune complexes to the luminal surface of the mucosa. (3)
References
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
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Phenotype
Phenotype caused by Genes