Search Ontology:
GO: Biological Process

marginal zone B cell differentiation

Term ID
GO:0002315
Synonyms
  • marginal zone B cell development
  • marginal zone B lymphocyte differentiation
  • marginal zone B-cell differentiation
  • marginal zone B-lymphocyte differentiation
Definition
The process in which a B cell in the spleen acquires the specialized features of a marginal zone B cell. Marginal zone B cells are localized in a distinct anatomical region of the spleen that represents the major antigen-filtering and scavenging area (by specialized macrophages resident there). It appears that they are preselected to express a BCR repertoire similar to B-1 B cells, biased toward bacterial cell wall constituents and senescent self-components (such as oxidized LDL). 0781735149
References
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
is a type of
Phenotype
Phenotype caused by Genes