cap-dependent translational initiation

Term ID

GO:0002191

Synonyms

Definition

The process where the cap structure, composed of a 7- methylguanosine (m7G) group and associated cap-binding proteins, located at the 5' end of an mRNA molecule, which serves as a molecular tag that marks the spot where the 40S ribosomal subunit, is recruited and will then scan in a 5' to 3' direction until an AUG codon is encountered in an appropriate sequence context to initiate mRNA translation. (2)

References

Ontology

GO: Biological Process    QuickGO    AmiGO