T cell mediated cytotoxicity

Term ID

GO:0001913

Synonyms

T cell mediated apoptosis
T cell mediated cell death
T cell mediated cell killing
T cell mediated cytolysis
T lymphocyte mediated cytotoxicity
T-cell mediated apoptosis
T-cell mediated cell death
T-cell mediated cell killing
T-cell mediated cytotoxicity
T-lymphocyte mediated cytotoxicity

Definition

The directed killing of a target cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors. (2)

References

Ontology

GO: Biological Process QuickGO AmiGO

Relationships

has parts: cytotoxic T cell degranulation

cytotoxic T cell degranulation Show first 5 Terms
is a type of: leukocyte mediated cytotoxicity T cell mediated immunity

leukocyte mediated cytotoxicity T cell mediated immunity Show first 5 Terms
has subtype: T cell mediated cytotoxicity directed against tumor cell target

T cell mediated cytotoxicity directed against tumor cell target Show first 5 Terms
inverse capable_of: CD4-positive, alpha-beta cytotoxic T cell CD8-positive, alpha-beta cytotoxic T cell cytotoxic T cell

CD4-positive, alpha-beta cytotoxic T cell CD8-positive, alpha-beta cytotoxic T cell cytotoxic T cell Show first 5 Terms
negatively regulated by: negative regulation of T cell mediated cytotoxicity

negative regulation of T cell mediated cytotoxicity Show first 5 Terms
positively regulated by: positive regulation of T cell mediated cytotoxicity

positive regulation of T cell mediated cytotoxicity Show first 5 Terms
regulated by: regulation of T cell mediated cytotoxicity

regulation of T cell mediated cytotoxicity Show first 5 Terms

Phenotype

Phenotype caused by Genes