Gi/o-coupled serotonin receptor activity

Term ID

GO:0001586

Synonyms

• 5-HT1 receptor activity
• serotonin receptor activity, coupled via Gi/o

Definition

Combining with serotonin and transmitting the signal across the membrane by activation of the Gi/o subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gi/o subunit subsequently inhibits adenylate cyclase and results in a decrease in cyclic AMP (cAMP) levels. 18571247

References

Ontology

GO: Molecular Function    QuickGO    AmiGO