progressive multifocal leukoencephalopathy

Term ID

DOID:643

Synonyms

• PML

Definition

A viral infectious disease that involves reactivation of JC polyomavirus in immune-compromised individuals which causes the loss of white matter (which is made up of myelin, a substance the surrounds and protects nerve fibers) in multiple areas of the brain. The symptoms include hemiparesis, aphasia, dysarthria, hemianopia, cognitive impairment and coma. (3)

References

• GARD:7468
• ICD10CM:A81.2
• ICD9CM:046.3
• MESH:D007968
• NCI:C26815
• SNOMEDCT_US_2023_03_01:22255007
• UMLS_CUI:C0023524

Ontology

Human Disease   ( DOID:643 )