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Human Disease

progressive multifocal leukoencephalopathy

Term ID
DOID:643
Synonyms
  • PML
Definition
A viral infectious disease that involves reactivation of JC polyomavirus in immune-compromised individuals which causes the loss of white matter (which is made up of myelin, a substance the surrounds and protects nerve fibers) in multiple areas of the brain. The symptoms include hemiparesis, aphasia, dysarthria, hemianopia, cognitive impairment and coma. (3)
References
  • GARD:7468
  • ICD10CM:A81.2
  • ICD9CM:046.3
  • MESH:D007968
  • NCI:C26815
  • SNOMEDCT_US_2023_03_01:22255007
  • UMLS_CUI:C0023524
Ontology
Human Disease   ( DOID:643 )
Relationships
is a type of
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Genes Involved
Zebrafish Models