Search Ontology:
Human Disease

MHC class II deficiency

Term ID
DOID:5812
Synonyms
  • bare lymphocyte syndrome type II
  • BLSII
  • SCID due to absent class II HLA antigens
Definition
A severe combined immunodeficiency that is characterized by deficiency of MHC class II molecules that causes lack of immune protection against bacteria, viruses, and fungi and thus causes early death in childhood, and has_material_basis_in autosomal recessive inheritance of mutation in the CIITA, RFX5, RFXANK, and RFXAP genes. (2)
References
Ontology
Human Disease   ( DOID:5812 )
Relationships
is a type of
Other Pages
Alliance (1)
Genes Involved
Zebrafish Models
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