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Human Disease

granulomatosis with polyangiitis

Term ID
DOID:12132
Synonyms
  • Necrotizing respiratory granulomatosis
  • Wegener granulomatosis, formerly
Definition
An autoimmune disease that is characterized by necrotizing granulomatous inflammation of the upper and lower respiratory tract, glomerulonephritis, vasculitis, and the presence of antineutrophil cytoplasmatic autoantibodies (ANCAs) in patient sera, and is located_in lung, located_in kidney, located_in skin resulting from an autoimmune attack by antineutrophil cytoplasmic antibodies against small and medium-size blood vessels. https://en.wikipedia.org/wiki/Granulomatosis_with_polyangiitis
References
  • GARD:7880
  • ICD10CM:M31.3
  • ICD9CM:446.4
  • MESH:D014890
  • MIM:608710
  • NCI:C3444
  • SNOMEDCT_US_2023_03_01:195353004
  • UMLS_CUI:C3495801
Ontology
Human Disease   ( DOID:12132 )
Relationships
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Genes Involved
Zebrafish Models