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Human Disease

Alzheimer's disease

Term ID
DOID:10652
Synonyms
  • Alzheimer disease
  • Alzheimers dementia
Definition
A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid. (3)
References
  • GARD:10254
  • ICD10CM:G30
  • ICD9CM:331.0
  • KEGG:05010
  • MESH:D000544
  • NCI:C2866
  • SNOMEDCT_US_2023_03_01:73768007
  • UMLS_CUI:C0002395
Ontology
Human Disease   ( DOID:10652 )
Relationships
is a type of
has subtype
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Genes Involved
Zebrafish Models