Search Ontology:
Human Disease

core binding factor acute myeloid leukemia

Term ID
DOID:0080796
Synonyms
Definition
An acute myeloid leukemia that is characterized by the presence of t(8;21)(q22;q22) or inv(16)(p13q22)/t(16;16)(p13;q22). These cytogenetic abnormalities result in disruption of the transcription factor CBF, which is a regulator of normal hematopoiesis. https://pubmed.ncbi.nlm.nih.gov/26980726/
References
  • NCI:C122688
Ontology
Human Disease   ( DOID:0080796 )
Relationships
is a type of
Other Pages
Alliance (1)
Genes Involved
Zebrafish Models
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