long QT syndrome 16

Term ID

DOID:0070533

Synonyms

• LQT16

Definition

A long QT syndrome characterized by perinatal onset of markedly prolonged corrected QT (QTc) interval, 2:1 atrioventricular (AV) block, and bradycardia or ventricular tachycardia (torsades de pointes) that has_material_basis_in heterozygous mutation in the CALM3 gene on chromosome 19q13.32. Syncope, cardiac arrest, and sudden death are common. (2)

References

• MIM:618782

Ontology

Human Disease   ( DOID:0070533 )