glucocorticoid-induced osteoporosis

Term ID

DOID:0060343

Synonyms

• steroid-induced osteoporosis

Definition

An osteoporosis caused by chronic glucocorticoid use. Glucocorticoids impair the replication, differentiation and function of osteoblasts and induce the apoptosis of mature osteoblasts and osteocytes; the also favor osteoclastogenesis leading to an increase in bone resorption. (2)

References

Ontology

Human Disease   ( DOID:0060343 )