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Cell Ontology

interstitial cell of Cajal

Term ID
CL:0002088
Synonyms
  • ICC
  • intestinal pacemaker cell
Definition
This is a cell found in the gastrointestinal tract of mammals and serves as a pacemaker that triggers gut contraction. ICCs mediate inputs from the enteric nervous system to smooth muscle cells and are thought to be the cells from which gastrointestinal stromal tumors (GISTs) arise. (2)
References
  • BTO:0003914
  • FMA:86573
Ontology
Cell Ontology
Relationships
is a type of
capable_of
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