CD8_alpha-negative CD11b-negative dendritic cell

Term ID

CL:0000998

Synonyms

DC.8-4-11b-
triple negative dendritic cell

Definition

CD8_alpha-negative CD11b-negative dendritic cell is a conventional dendritic cell that is CD11b-negative, CD4-negative CD8_alpha-negative and is CD205-positive. This cell is able to cross- present antigen to CD8-alpha-positive T cells. http:www.immgen.org/index_content.html

References

Ontology

Cell Ontology

Relationships

develops from: pre-conventional dendritic cell

pre-conventional dendritic cell Show first 5 Terms
is a type of: conventional dendritic cell myeloid leukocyte

conventional dendritic cell myeloid leukocyte Show first 5 Terms
has subtype: immature CD8_alpha-negative CD11b-negative dendritic cell mature CD8_alpha-negative CD11b-negative dendritic cell

immature CD8_alpha-negative CD11b-negative dendritic cell mature CD8_alpha-negative CD11b-negative dendritic cell Show first 5 Terms
capable_of: antigen processing and presentation of peptide antigen via MHC class I

antigen processing and presentation of peptide antigen via MHC class I Show first 5 Terms
has_plasma_membrane_part: lymphocyte antigen 75

lymphocyte antigen 75 Show first 5 Terms
lacks_plasma_membrane_part: CD4 molecule integrin alpha-M T-cell surface glycoprotein CD8 alpha chain

CD4 molecule integrin alpha-M T-cell surface glycoprotein CD8 alpha chain Show first 5 Terms