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Cell Ontology

naive B cell

Term ID

CL:0000788

Synonyms

naive B lymphocyte
naive B-cell
naive B-lymphocyte

Definition

A naive B cell is a mature B cell that has the phenotype surface IgD-positive, surface IgM-positive, CD20-positive, CD27-negative and that has not yet been activated by antigen in the periphery. (6)

References

Ontology

Cell Ontology

Relationships

develops from: transitional stage B cell

transitional stage B cell Show first 5 Terms
is a type of: mature B cell

mature B cell Show first 5 Terms
has subtype: CD38-negative naive B cell CD38-positive naive B cell

CD38-negative naive B cell CD38-positive naive B cell Show first 5 Terms
has_not_completed: B cell affinity maturation

B cell affinity maturation Show first 5 Terms
has_plasma_membrane_part: IgD immunoglobulin complex IgM immunoglobulin complex membrane-spanning 4-domains subfamily A member 1

IgD immunoglobulin complex IgM immunoglobulin complex membrane-spanning 4-domains subfamily A member 1 Show first 5 Terms
lacks_plasma_membrane_part: CD27 molecule

CD27 molecule Show first 5 Terms