memory B cell

Term ID

CL:0000787

Synonyms

memory B lymphocyte
memory B-cell
memory B-lymphocyte

Definition

A memory B cell is a mature B cell that is long-lived, readily activated upon re-encounter of its antigenic determinant, and has been selected for expression of higher affinity immunoglobulin. This cell type has the phenotype CD19-positive, CD20-positive, MHC Class II-positive, and CD138-negative. (4)

References

Ontology

Cell Ontology

Relationships

is a type of: mature B cell

mature B cell Show first 5 Terms
has subtype: Bm5 B cell class switched memory B cell double negative memory B cell IgD-negative memory B cell IgM memory B cell ... Show All 6 Terms

Bm5 B cell class switched memory B cell double negative memory B cell IgD-negative memory B cell IgM memory B cell unswitched memory B cell Show first 5 Terms
has_completed: B cell affinity maturation

B cell affinity maturation Show first 5 Terms
has_plasma_membrane_part: CD27 molecule membrane-spanning 4-domains subfamily A member 1 MHC class II protein complex

CD27 molecule membrane-spanning 4-domains subfamily A member 1 MHC class II protein complex Show first 5 Terms
lacks_plasma_membrane_part: syndecan-1

syndecan-1 Show first 5 Terms