Langerhans cell

Term ID

CL:0000453

Synonyms

• Langerhans' cell
• LC

Definition

Langerhans cell is a conventional dendritic cell that has plasma membrane part CD207. A Langerhans cell is a stellate dendritic cell of myeloid origin, that appears clear on light microscopy and has a dark-staining, indented nucleus and characteristic inclusions (Birbeck granules) in the cytoplasm; Langerhans cells are found principally in the stratum spinosum of the epidermis, but they also occur in other stratified epithelia and have been identified in the lung, lymph nodes, spleen, and thymus. (3)

References

• BTO:0000705
• CALOHA:TS-2375
• FMA:63072

Ontology

Cell Ontology