tolazamide

Term ID

CHEBI:9613

Synonyms

• 1-(hexahydro-1-azepinyl)-3-p-tolylsulfonylurea
• 1-(hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)urea
• 4-(p-tolylsulfonyl)-1,1-hexamethylenesemicarbazide
• BRN 1323565
• CCRIS 591
• Diabewas
• EINECS 214-588-3
• N-(azepan-1-ylcarbamoyl)-4-methylbenzenesulfonamide
• N-(p-toluenesulfonyl)-N'-hexamethyleniminourea
• N-{[(hexahydro-1H-azepin-1-yl)-amino]carbonyl}-4-methylbenzenesulfonamide
• Norglycin
• tolazamida
• tolazamide
• tolazamidum
• Tolinase
• U 17835
• U-17835

Definition

An N-sulfonylurea that is 1-tosylurea in which a hydrogen attached to the nitrogen at position 3 is replaced by an azepan-1-yl group. A hypoglycemic agent, it is used for the treatment of type 2 diabetes mellitus.

References

• CAS:1156-19-0
• DrugBank:DB00839
• Drug_Central:2694
• HMDB:HMDB0014977
• KEGG:D00379
• LINCS:LSM-2699
• PMID:15901207
• PMID:8237731
• Patent:GB887886
• Reaxys:1323565
• Wikipedia:Tolazamide

Ontology

ChEBI  ( EBI )

Resources

CTD