UNC0638

Term ID

CHEBI:95074

Synonyms

2-cyclohexyl-6-methoxy-N-(1-propan-2-yl-4-piperidinyl)-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamine
2-cyclohexyl-6-methoxy-N-(1-propan-2-ylpiperidin-4-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine
2-cyclohexyl-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamin
2-cyclohexyl-6-methoxy-N-[1-(propan-2-yl)piperidin-4-yl]-7-[3-(pyrrolidin-1-yl)propoxy]quinazolin-4-amine
2-cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy) quinazolin-4-amine
UNC 0638
UNC-0638

Definition

A member of the class of quinazolines that is quinazoline substituted by cyclohexyl, [1-(propan-2-yl)piperidin-4-yl]amino, methoxy, and 3-(pyrrolidin-1-yl)propoxy groups at positions 2, 4, 6 and 7, respectively. It inhibits G9a and GLP histone methyltransferase activity (IC50 = <15 nM and <20 nM, respectively).

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: aminopiperidine aromatic ether pyrrolidines quinazolines secondary amino compound ... Show All 6 Terms

aminopiperidine aromatic ether pyrrolidines quinazolines secondary amino compound tertiary amino compound Show first 5 Terms
has_role: antineoplastic agent antiviral agent

antineoplastic agent antiviral agent Show first 5 Terms

Phenotype

Phenotype resulting from UNC0638

Phenotype where environments contain UNC0638

Phenotype modified by environments containing UNC0638

Human Disease Model