Search Ontology:
ChEBI
dinaciclib
- Term ID
- CHEBI:95060
- Synonyms
-
- (2S)-1-[3-ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]-2-piperidineethanol
- 2-[(2S)-1-(3-ethyl-7-{[(1-oxidopyridin-3-yl)methyl]amino}pyrazolo[1,5-a]pyrimidin-5-yl)piperidin-2-yl]ethanol
- 2-[(2S)-1-[3-ethyl-7-[(1-oxidopyridin-1-ium-3-yl)methylamino]pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-2-yl]ethanol
- dinaciclib
- dinaciclibum
- MK 7965
- MK-7965
- MK7965
- SCH 727965
- SCH-727965
- SCH727965
- Definition
- A pyrazolopyrimidine that is pyrazolo[1,5-a]pyrimidine substituted by ethyl, (2S)-2-(2-hydroxyethyl)piperidin-1-yl, and [(1-oxidopyridin-3-yl)methyl]amino groups at positions 3, 5, and 7, respectively. It is a potent pan-cyclin dependent kinase inhibitor that exhibits antineoplastic activity.
- References
-
- CAS:779353-01-4
- DrugBank:DB12021
- KEGG:D09604
- LINCS:LSM-6306
- PDBeChem:1QK
- PMID:20663931
- PMID:21490307
- PMID:22315240
- PMID:23949430
- PMID:24007471
- PMID:24388167
- PMID:24393852
- PMID:24568369
- PMID:24900195
- PMID:25947565
- PMID:26018905
- PMID:27496135
- PMID:30472117
- PMID:31207099
- PMID:32269732
- PMID:32944844
- PMID:34972202
- PMID:35170591
- PMID:35884614
- PMID:36505806
- PMID:36586018
- PMID:36700399
- PMID:36979907
- PMID:37104883
- PMID:37270540
- PMID:37694833
- PMID:37703185
- PMID:37704591
- PMID:38135130
- PMID:38254859
- PMID:38438856
- PMID:38474332
- PMID:38480681
- PMID:38545471
- PMID:38685605
- PMID:38786326
- PMID:38845263
- Wikipedia:Dinaciclib
- Ontology
- ChEBI ( EBI )
- is a type of
- has_role
-
Show All 6 Terms
Show first 5 Terms
Phenotype
Phenotype resulting from dinaciclib
Phenotype where environments contain dinaciclib
Phenotype modified by environments containing dinaciclib
Human Disease / Model Data