Search Ontology:
ChEBI
pimasertib
- Term ID
- CHEBI:94793
- Synonyms
-
- AS 703026
- AS-703026
- AS703026
- MSC 1936369B
- MSC-1236369B
- MSC1936369B
- N-[(2S)-2,3-dihydroxypropyl]-3-(2-fluoro-4-iodoanilino)-4-pyridinecarboxamide
- N-[(2S)-2,3-dihydroxypropyl]-3-(2-fluoro-4-iodoanilino)pyridine-4-carboxamide
- pimasertib
- pimasertibum
- SAR 245509
- SAR-245509
- SAR245509
- Definition
- A secondary carboxamide resulting from the formal condensation of the carboxy group of 3-(2-fluoro-4-iodoanilino)pyridine-4-carboxylic acid with the amino group of (2S)-3-aminopropane-1,2-diol. It is a potent inhibitor of the mitogen-activated protein kinases MEK1 and MEK2 with potential antineoplastic activity.
- References
-
- CAS:1236699-92-5
- DrugBank:DB14904
- KEGG:D10426
- LINCS:LSM-5946
- PDBeChem:QOA
- PMID:20331454
- PMID:24051957
- PMID:25989270
- PMID:26033306
- PMID:26381508
- PMID:26444523
- PMID:26640591
- PMID:26657199
- PMID:26924269
- PMID:26961147
- PMID:27179113
- PMID:27179114
- PMID:27483391
- PMID:27934635
- PMID:28151716
- PMID:28194539
- PMID:28289865
- PMID:29338133
- PMID:29488172
- PMID:29756206
- PMID:30425349
- PMID:30585255
- PMID:30848427
- PMID:31482223
- PMID:31586300
- PMID:31870556
- PMID:32610581
- PMID:33170484
- PMID:33211315
- PMID:34470822
- PMID:37097377
- Ontology
- ChEBI ( EBI )
- is a type of
- has_role
-
Show All 8 Terms
Show first 5 Terms
Phenotype
Phenotype resulting from pimasertib
Phenotype where environments contain pimasertib
Phenotype modified by environments containing pimasertib
Human Disease / Model Data