Search Ontology:
ChEBI
6-chloro-7-[2-(4-morpholinyl)ethylamino]quinoline-5,8-dione
- Term ID
- CHEBI:92053
- Synonyms
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- 6-chloro-7-(2-morpholin-4-yl-ethylamino)quinoline-5,8-dione
- 6-chloro-7-(2-morpholin-4-ylethylamino)-quinoline-5,8-dione
- 6-chloro-7-[[2-(4-morpholinyl)ethyl]amino]-5,8-quinolinedione
- 6-chloro-7-{[2-(morpholin-4-yl)ethyl]amino}quinoline-5,8-dione
- CDC25 phosphatase inhibitor II
- DA-3003-01
- DA-3003-1
- DA3003-1
- NSC 663284
- NSC-663284
- NSC663284
- SPS8I1
- Definition
- A quinolone that is quinoline-5,8-dione substituted by chloro and [2-(morpholin-4-yl)ethyl]amino groups at positions 6 and 7, respectively. It is a potent and irreversible inhibitor of Cdc25 isoforms.
- References
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- CAS:383907-43-5
- DrugBank:DB17038
- LINCS:LSM-2042
- PDBeChem:CQD
- PMID:11708908
- PMID:12356752
- PMID:14718602
- PMID:14988404
- PMID:16155209
- PMID:17970046
- PMID:18245669
- PMID:18699726
- PMID:28994029
- PMID:29186901
- PMID:31541869
- PMID:34426152
- PMID:36642961
- PMID:37302341
- PMID:38255157
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
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Phenotype
Phenotype resulting from 6-chloro-7-[2-(4-morpholinyl)ethylamino]quinoline-5,8-dione
Phenotype where environments contain 6-chloro-7-[2-(4-morpholinyl)ethylamino]quinoline-5,8-dione
Phenotype modified by environments containing 6-chloro-7-[2-(4-morpholinyl)ethylamino]quinoline-5,8-dione
Human Disease Model