Search Ontology:
ChEBI

tivozanib

Term ID
CHEBI:91327
Synonyms
  • 1-[2-chloro-4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-3-(5-methyl-3-isoxazolyl)urea
  • 1-{2-chloro-4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-3-(5-methyl-1,2-oxazol-3-yl)urea
  • AV 951
  • AV-951
  • AV951
  • Kil 8951
  • KIL-8951
  • KRN 951
  • KRN-951
  • KRN951
  • N-[2-chloro-4-[(6,7-dimethoxy-4-quinolyl)oxy]phenyl]-N'-(5-methyl-3-isoxazolyl)urea
  • tivozanib
  • tivozanibum
Definition
A member of the class of quinolines that is 6,7-dimethoxyquinoline substituted by a 3-chloro-4-{[(5-methyl-1,2-oxazol-3-yl)carbamoyl]amino}phenoxy group at position 4. It is a potent and selective inhibitor of VEGF receptor tyrosine kinases and was previously in clinical development for the treatment of metastatic renal cell carcinoma.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from tivozanib
Phenotype where environments contain tivozanib
Phenotype modified by environments containing tivozanib
Human Disease / Model Data
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