ixazomib citrate

Term ID

CHEBI:90939

Synonyms

2,2'-{2-[(1R)-1-{[N-(2,5-dichlorobenzoyl)glycyl]amino}-3-methylbutyl]-5-oxo-1,3,2-dioxaborolane-4,4-diyl}diacetic acid
MLN 9708
MLN9708
NINLARO

Definition

A glycine derivative that is the amide obtained by formal condensation of the carboxy group of N-(2,5-dichlorobenzoyl)glycine with the amino group of 2,2'-{2-[(1R)-1-amino-3-methylbutyl]-5-oxo-1,3,2-dioxaborolane-4,4-diyl}diacetic acid. A prodrug for ixazomib that is used in combination therapy for treatment of multiple myeloma.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: 1,3,2-dioxaborolane benzamides dichlorobenzene glycine derivative oxo dicarboxylic acid

1,3,2-dioxaborolane benzamides dichlorobenzene glycine derivative oxo dicarboxylic acid Show first 5 Terms
has_functional_parent: ixazomib

ixazomib Show first 5 Terms
has_role: antineoplastic agent apoptosis inducer orphan drug prodrug proteasome inhibitor

antineoplastic agent apoptosis inducer orphan drug prodrug proteasome inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from ixazomib citrate

Phenotype where environments contain ixazomib citrate

Phenotype modified by environments containing ixazomib citrate

Human Disease / Model Data