Search Ontology:
ChEBI
tenofovir alafenamide
- Term ID
- CHEBI:90926
- Synonyms
-
- GS 7340
- GS-7340
- propan-2-yl N-[(S)-({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)(phenoxy)phosphoryl]-L-alaninate
- TAF
- tenofovir alafenamide
- Definition
- An L-alanine derivative that is isopropyl L-alaninate in which one of the amino hydrogens is replaced by an (S)-({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)(phenoxy)phosphoryl group. A prodrug for tenofovir, it is used (as the fumarate salt) in combination therapy for the treatment of HIV-1 infection.
- References
-
- CAS:379270-37-8
- DrugBank:DB09299
- Drug_Central:4944
- KEGG:D10428
- Reaxys:8948831
- Wikipedia:Tenofovir_alafenamide
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_functional_parent
-
- has_role
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- inverse is_conjugate_acid_of
-
- is_conjugate_base_of
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Phenotype
Phenotype resulting from tenofovir alafenamide
Phenotype where environments contain tenofovir alafenamide
Phenotype modified by environments containing tenofovir alafenamide
Human Disease Model