Search Ontology:
ChEBI
sonidegib
- Term ID
- CHEBI:90863
- Synonyms
-
- Erismodegib
- LDE 225
- LDE-225
- LDE225
- N-[6-(cis-2,6-dimethylmorpholin-4-yl)pyridin-3-yl]-2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxamide
- NVP-LDE 225
- NVP-LDE225
- rel-N-{6-[(2R,6S)-2,6-dimethylmorpholin-4-yl]pyridin-3-yl}-2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxamide
- sonidegib
- Definition
- A member of the classo of biphenyls that is the amide obtained by formal condensation of the carboxy group of 2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxylic acid with the amino group of 6-(2,6-dimethylmorpholin-4-yl)pyridin-3-amine. Used (as its phosphate salt) for treatment of locally advanced basal cell carcinoma.
- References
-
- CAS:956697-53-3
- Drug_Central:5008
- KEGG:D10119
- LINCS:LSM-4938
- PMID:23482671
- PMID:23935925
- PMID:24523439
- PMID:24817600
- PMID:25093491
- PMID:25216523
- PMID:25473003
- PMID:25981810
- PMID:26106586
- PMID:26483188
- PMID:26516158
- PMID:26546616
- Reaxys:19431762
- Wikipedia:Sonidegib
- Ontology
- ChEBI ( EBI )
- is a type of
- has_role
-
- inverse has_part
-
Phenotype
Phenotype resulting from sonidegib
Phenotype where environments contain sonidegib
Phenotype modified by environments containing sonidegib
Human Disease Model