sonidegib

Term ID

CHEBI:90863

Synonyms

Erismodegib
LDE 225
LDE-225
LDE225
N-[6-(cis-2,6-dimethylmorpholin-4-yl)pyridin-3-yl]-2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxamide
NVP-LDE 225
NVP-LDE225
rel-N-{6-[(2R,6S)-2,6-dimethylmorpholin-4-yl]pyridin-3-yl}-2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxamide
sonidegib

Definition

A member of the classo of biphenyls that is the amide obtained by formal condensation of the carboxy group of 2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxylic acid with the amino group of 6-(2,6-dimethylmorpholin-4-yl)pyridin-3-amine. Used (as its phosphate salt) for treatment of locally advanced basal cell carcinoma.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: aminopyridine aromatic ether benzamides biphenyls morpholines ... Show All 7 Terms

aminopyridine aromatic ether benzamides biphenyls morpholines organofluorine compound tertiary amino compound Show first 5 Terms
has_role: antineoplastic agent Hedgehog signaling pathway inhibitor SMO receptor antagonist

antineoplastic agent Hedgehog signaling pathway inhibitor SMO receptor antagonist Show first 5 Terms
inverse has_part: sonidegib phosphate

sonidegib phosphate Show first 5 Terms

Phenotype

Phenotype resulting from sonidegib

Phenotype where environments contain sonidegib

Phenotype modified by environments containing sonidegib

Human Disease / Model Data