savinin

Term ID

CHEBI:9044

Synonyms

• (-)-hibalactone
• (-)-savinin
• (3E,4R)-4-(1,3-benzodioxol-5-ylmethyl)-3-(1,3-benzodioxol-5-ylmethylene)dihydro-2(3H)-furanone
• (3E,4R)-4-(1,3-benzodioxol-5-ylmethyl)-3-(1,3-benzodioxol-5-ylmethylidene)dihydrofuran-2(3H)-one
• (3E,4R)-4-[(2H-1,3-benzodioxol-5-yl)methyl]-3-[(2H-1,3-benzodioxol-5-yl)methylidene]oxolan-2-one
• hibalactone
• savinin

Definition

A lignan that is dihydrofuran-2(3H)-one (gamma-butyrolactone) substituted by a 1,3-benzodioxol-5-ylmethylidene group at position 3 and a 1,3-benzodioxol-5-ylmethyl group at position 4 (the 3E,4R-isomer). It exhibits antiviral activity against SARS-CoV-2.

References

• CAS:493-95-8
• Chemspider:4445161
• KEGG:C10880
• KNApSAcK:C00002624
• PMID:11217086
• PMID:12392817
• PMID:15852488
• PMID:17291735
• PMID:17663539
• PMID:18563665
• PMID:22497733
• PMID:27041873
• PMID:27714269
• PMID:28903179
• PMID:30915141
• PMID:32786879
• PMID:33089730
• PMID:33101023
• PMID:34313197
• PMID:34424612
• PMID:6539809

Ontology

ChEBI  ( EBI )