Search Ontology:
ChEBI
PLX-4720
- Term ID
- CHEBI:90295
- Synonyms
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- N-[3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl]propane-1-sulfonamide
- N-{3-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide
- PLX 4720
- PLX4720
- Definition
- A pyrrolopyridine that is vemurafenib in which the p-chlorophenyl group has been replaced by chlorine. It is a potent and selective inhibitor of the Raf kinase B-Raf(V600E).
- References
-
- CAS:918505-84-7
- LINCS:LSM-1049
- PDBeChem:324
- PMID:20818433
- PMID:21088259
- PMID:21134546
- PMID:21355020
- PMID:21738740
- PMID:22858545
- PMID:22941213
- PMID:24735766
- PMID:25544599
- PMID:26347528
- PMID:26456124
- Reaxys:12833018
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Phenotype
Phenotype resulting from PLX-4720
Phenotype where environments contain PLX-4720
Phenotype modified by environments containing PLX-4720
Human Disease / Model Data