PHA-665752

Term ID

CHEBI:90197

Synonyms

(3Z)-5-[(2,6-dichlorobenzyl)sulfonyl]-3-[(3,5-dimethyl-4-{[(2R)-2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl]carbonyl}-1H-pyrrol-2-yl)methylidene]-1,3-dihydro-2H-indol-2-one
PHA 665752
PHA665752

Definition

A member of the class of indolones that is 1,3-dihydro-2H-indol-2-one which is substituted by a (2,6-dichlorobenzyl)sulfonyl group at position 5 and by a (1H-pyrrol-2-yl)methylidene group at position 2, the pyrrole ring of which is substituted by methyl groups at positions 3 and 5, and by a [2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl]carbonyl group at position 4 (the Z,R isomer).

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: dichlorobenzene enamide indolones N-acylpyrrolidine pyrrolecarboxamide ... Show All 8 Terms

dichlorobenzene enamide indolones N-acylpyrrolidine pyrrolecarboxamide secondary carboxamide sulfone tertiary carboxamide Show first 5 Terms
has_role: antineoplastic agent c-Met tyrosine kinase inhibitor

antineoplastic agent c-Met tyrosine kinase inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from PHA-665752

Phenotype where environments contain PHA-665752

Phenotype modified by environments containing PHA-665752

Human Disease / Model Data