quinapril hydrochloride

Term ID

CHEBI:8714

Synonyms

• (3S)-2-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride
• (3S)-2-{(2S)-2-[(1S)-1-ethoxycarbonyl-3-phenylpropylamino]propanoyl}-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride
• (3S)-2-{N-[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl}-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride
• Accupril
• Accuprin
• Accupro
• Acequin
• Acuitel
• CI-906
• Hemokvin
• Korec
• Quinapril hydrochloride
• Quinazil

Definition

A hydrochloride resulting from the reaction of equimolar amounts of quinapril and hydrogen chloride. A prodrug for quinaprilat hydrochloride (by hydrolysis of the ethyl ester to the corresponding carboxylic acid), it is used as an angiotensin-converting enzyme inhibitor (ACE inhibitor) for the treatment of hypertension and congestive heart failure.

References

• Beilstein:5699760
• CAS:82586-55-8
• Drug_Central:2340
• KEGG:C07340
• KEGG:D00459
• PMID:12749406
• PMID:16193811
• PMID:24081473
• PMID:29310224
• PMID:8959644
• Patent:US7482361
• Patent:WO2004087671

Ontology

ChEBI  ( EBI )

Resources

CTD