pyrimethamine

Term ID

CHEBI:8673

Synonyms

• 2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine
• 2,4-Diamino-5-(p-chlorophenyl)-6-ethylpyrimidine
• 2,4-Diamino-5-chlorophenyl-6-ethylpyrimidine
• 5-(4'-Chlorophenyl)-2,4-diamino-6-ethylpyrimidine
• 5-(4-Chlorophenyl)-6-ethyl-2,4-diaminopyrimidine
• 5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine
• 5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine
• CD
• Chloridine
• Chloridyn
• Diaminopyritamin
• Ethylpyrimidine
• pirimetamina
• Primethamine
• pyrimethamine
• pyrimethaminum

Definition

An aminopyrimidine that is pyrimidine-2,4-diamine which is substituted at position 5 by a p-chlorophenyl group and at position 6 by an ethyl group. It is a folic acid antagonist used as an antimalarial or with a sulfonamide to treat toxoplasmosis.

References

• Beilstein:219864
• CAS:58-14-0
• DrugBank:DB00205
• HMDB:HMDB0014350
• KEGG:C07391
• KEGG:D00488
• LINCS:LSM-3967
• PDBeChem:CP6
• PMID:11257045
• PMID:11313656
• PMID:12543697
• PMID:16157660
• PMID:19435820
• PMID:28166217
• PMID:3377143
• Reaxys:219864
• VSDB:1912
• Wikipedia:Pyrimethamine

Ontology

ChEBI  ( EBI )

Resources

CTD