palonosetron

Term ID

CHEBI:85161

Synonyms

(3aS)-2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one
2-(1-Azabicyclo(2.2.2)oct-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benz(de)isoquinolin-1-one
palonosetron
palonosetronum

Definition

An organic heterotricyclic compound that is an antiemetic used (as its hydrochloride salt) in combination with netupitant (under the trade name Akynzeo) to treat nausea and vomiting in patients undergoing cancer chemotherapy.

References

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: azabicycloalkane delta-lactam organic heterotricyclic compound

azabicycloalkane delta-lactam organic heterotricyclic compound Show first 5 Terms
has_role: antiemetic serotonergic antagonist

antiemetic serotonergic antagonist Show first 5 Terms
inverse is_conjugate_acid_of: palonosetron(1+)

palonosetron(1+) Show first 5 Terms
is_conjugate_base_of: palonosetron(1+)

palonosetron(1+) Show first 5 Terms

Phenotype

Phenotype resulting from palonosetron

Phenotype where environments contain palonosetron

Phenotype modified by environments containing palonosetron

Human Disease Model