Search Ontology:
ChEBI
torin 1
- Term ID
- CHEBI:84327
- Synonyms
-
- 1-[4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl]-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one
- torin1
- Definition
- A member of the class of pyridoquinolines that is 9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2-one bearing an additional 4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl substituent at position 1. It is a potent inhibitor of mTOR and exhibits anti-cancer properties.
- References
-
- LINCS:LSM-1079
- PMID:20860370
- PMID:24424027
- PMID:25339775
- Reaxys:20268275
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Phenotype
Phenotype resulting from torin 1
Phenotype where environments contain torin 1
Phenotype modified by environments containing torin 1
Human Disease Model