pristinamycin IA

Term ID

CHEBI:8417

Synonyms

• 4-[4-(Dimethylamino)-N-methyl-L-phenylalanine]virginiamycin S1
• Antibiotic PA 114B
• Antibiotic PA 114B1
• Mikamycin B
• N-[(6R,9S,10R,13S,15aS,22S,24aS)-22-{[4-(dimethylamino)phenyl]methyl}-6-ethyl-10,23-dimethyl-5,8,12,15,17,21,24-heptaoxo-13-phenyldocosahydro-12H-pyrido[2,1-f]pyrrolo[2,1-l][1,4,7,10,13,16]oxapentaazacyclononadecin-9-yl]-3-hydroxypyridine-2-carboxamide
• NSC 92554
• Ostreogrycin B
• Pristinamycin IA
• Streptogramin B
• Vernamycin B alpha

Definition

A cyclodepsipeptide that is (together with pristinamycin IIA) a component of pristinamycin, an oral streptogramin antibiotic produced by Streptomyces pristinaespiralis. Pristinamycin exhibits bactericidal activity against Gram positive organisms including methicillin-resistant Staphylococcus aureus.

References

• CAS:3131-03-1
• KEGG:C11615
• KNApSAcK:C00018680
• Reaxys:78387
• Wikipedia:Pristinamycin_IA

Ontology

ChEBI  ( EBI )

Resources

CTD