vorapaxar sulfate

Term ID

CHEBI:83314

Synonyms

2-[(E)-2-{(3R,3aS,4S,4aR,7R,8aR,9aR)-7-[(ethoxycarbonyl)amino]-3-methyl-1-oxododecahydronaphtho[2,3-c]furan-4-yl}ethenyl]-5-(3-fluorophenyl)pyridinium hydrogen sulfate
ethyl [(1R,3aR,4aR,6R,8aR,9S,9aS)-9-{(E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethenyl}-1-methyl-3-oxododecahydronaphtho[2,3-c]furan-6-yl]carbamate sulfate
Sch 530348
vorapaxar monosulfate
ZONTIVITY

Definition

An organic sulfate salt obtained by combining vorapaxar with one molar equivalent of sulfuric acid. A protease-activated receptor-1 antagonist used for the reduction of thrombotic cardiovascular events in patients with a history of myocardial infarction (MI) or with peripheral arterial disease. It has been shown to reduce the rate of a combined endpoint of cardiovascular death, MI, stroke and urgent coronary revascularisation.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: organic sulfate salt

organic sulfate salt Show first 5 Terms
has_part: vorapaxar(1+)

vorapaxar(1+) Show first 5 Terms
has_role: cardiovascular drug platelet aggregation inhibitor protease-activated receptor-1 antagonist

cardiovascular drug platelet aggregation inhibitor protease-activated receptor-1 antagonist Show first 5 Terms

Phenotype

Phenotype resulting from vorapaxar sulfate

Phenotype where environments contain vorapaxar sulfate

Phenotype modified by environments containing vorapaxar sulfate

Human Disease / Model Data