nemadipine-A

Term ID

CHEBI:78546

Synonyms

diethyl 2,6-dimethyl-4-(pentafluorophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
nemadipine A

Definition

A dihydropyridine that is that is 1,4-dihydropyridine which is substituted at positions 2 and 6 by methyl groups, at positions 3 and 5 by ethoxycarbonyl groups, and at position 4 by a pentafluorophenyl group. An L-type calcium channel alpha1-subunit antagonist. When exposed to the microscopic soil nematode Caenorhabditis elegans, nemadipine-A induces a variety of defects including those affecting morphology and egg laying.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: dicarboxylic acids and O-substituted derivatives diester dihydropyridine ethyl ester pentafluorobenzenes

dicarboxylic acids and O-substituted derivatives diester dihydropyridine ethyl ester pentafluorobenzenes Show first 5 Terms
has_role: calcium channel blocker

calcium channel blocker Show first 5 Terms

Phenotype

Phenotype resulting from nemadipine-A

Phenotype where environments contain nemadipine-A

Phenotype modified by environments containing nemadipine-A

Human Disease / Model Data