Search Ontology:
ChEBI
tafamidis
- Term ID
- CHEBI:78538
- Synonyms
-
- 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid
- 2-(3,5-dichlorophenyl)benzoxazole-6-carboxylic acid
- Fx-1006
- tafamidis
- tafamidisum
- Definition
- A member of the class of 1,3-benzoxazoles that is 1,3-benzoxazole-6-carboxylic acid in which the hydrogen at position 2 is replaced by a 3,5-dichlorophenyl group. Used (as its meglumine salt) for the amelioration of transthyretin-related hereditary amyloidosis.
- References
-
- CAS:594839-88-0
- Drug_Central:4192
- KEGG:D09673
- PDBeChem:3MI
- PMID:22378262
- PMID:22645360
- PMID:22645721
- PMID:22843282
- PMID:23569001
- PMID:23834402
- PMID:23974642
- PMID:24000164
- PMID:24101373
- PMID:24749898
- PMID:24998820
- PMID:24998822
- PMID:24998826
- PMID:25003808
- PMID:25022953
- Patent:WO2011131661
- Patent:WO2013060668
- Reaxys:9496624
- Wikipedia:Tafamidis
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
- inverse is_conjugate_base_of
-
- is_conjugate_acid_of
-
Phenotype
Phenotype resulting from tafamidis
Phenotype where environments contain tafamidis
Phenotype modified by environments containing tafamidis
Human Disease Model