Search Ontology:
ChEBI
dorsomorphin
- Term ID
- CHEBI:78510
- Synonyms
-
- 6-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine
- compound C
- Definition
- A pyrazolopyrimidine that is pyrazolo[1,5-a]pyrimidine which is substituted at positions 3 and 6 by pyridin-4-yl and p-[2-(piperidin-1-yl)ethoxy]phenyl groups, respectively. It is a potent, selective, reversible, and ATP-competitive inhibitor of AMPK (AMP-activated protein kinase, EC 2.7.11.31) and a selective inhibitor of bone morphogenetic protein (BMP) signaling.
- References
-
- CAS:866405-64-3
- DrugBank:DB08597
- LINCS:LSM-3207
- PDBeChem:TAK
- PMID:18026094
- PMID:18682835
- PMID:19996563
- PMID:20691279
- PMID:21384475
- PMID:21543851
- PMID:21988724
- PMID:23526253
- PMID:23936500
- PMID:24280125
- PMID:24396733
- PMID:35782765
- PMID:38500971
- Reaxys:11725482
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Phenotype
Phenotype resulting from dorsomorphin
Phenotype where environments contain dorsomorphin
Phenotype modified by environments containing dorsomorphin
Human Disease Model