Search Ontology:
ChEBI
PP2
- Term ID
- CHEBI:78331
- Synonyms
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- 1-tert-butyl-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
- AG 1879
- AG-1879
- AG1879
- Definition
- A member of the class of pyrazolopyrimidine that is pyrazolo[3,4-d]pyrimidin-4-amine bearing additional tert-butyl and 4-chlorophenyl substituents at positions 1 and 3 respectively. It is a potent ATP-competitive inhibitor of the Src family of protein tyrosine kinases.
- References
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- CAS:172889-27-9
- LINCS:LSM-4153
- PDBeChem:PP2
- PMID:22363408
- PMID:24183378
- PMID:24566462
- PMID:24735922
- PMID:31340912
- Reaxys:9409964
- Wikipedia:PP2_(kinase_inhibitor)
- Ontology
- ChEBI ( EBI )
- is a type of
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- has_role
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Phenotype
Phenotype resulting from PP2
Phenotype where environments contain PP2
Phenotype modified by environments containing PP2
Human Disease Model