huperzine A

Term ID

CHEBI:78330

Synonyms

(-)-huperazine A
(-)-selagine
(5R,9R,11E)-5-amino-11-ethylidene-5,6,9,10-tetrahydro-7-methyl-5,9-methanocycloocta[b]pyridin-2(1H)-one
(5R,9R,11E)-5-amino-11-ethylidene-7-methyl-5,6,9,10-tetrahydro-5,9-methanocycloocta[b]pyridin-2(1H)-one
Hup A
HupA
huperzine-A
hupzine A
kimpukan A
selagine

Definition

A sesquiterpene alkaloid isolated from a club moss Huperzia serrata that has been shown to exhibit neuroprotective activity. It is also an effective inhibitor of acetylcholinesterase and has attracted interest as a therapeutic candidate for Alzheimer's disease.

References

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: organic heterotricyclic compound primary amino compound pyridone sesquiterpene alkaloid

organic heterotricyclic compound primary amino compound pyridone sesquiterpene alkaloid Show first 5 Terms
has_role: EC 3.1.1.7 (acetylcholinesterase) inhibitor neuroprotective agent nootropic agent plant metabolite

EC 3.1.1.7 (acetylcholinesterase) inhibitor neuroprotective agent nootropic agent plant metabolite Show first 5 Terms
inverse is_conjugate_acid_of: huperzine A(1+)

huperzine A(1+) Show first 5 Terms
is_conjugate_base_of: huperzine A(1+)

huperzine A(1+) Show first 5 Terms

Phenotype

Phenotype resulting from huperzine A

Phenotype where environments contain huperzine A

Phenotype modified by environments containing huperzine A

Human Disease Model