Search Ontology:
ChEBI

indoprofen

Term ID
CHEBI:76162
Synonyms
  • 1-Oxo-2-(p-((alpha-methyl)carboxymethyl)phenyl)isoindoline
  • 2-(4-(1-Carboxyethyl)phenyl)-1-isoindolinone
  • 2-[4-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)phenyl]propanoic acid
  • alpha-(4-(1-Oxo-2-isoindolinyl)phenyl)propionic acid
  • indoprofen
  • indoprofene
  • indoprofeno
  • indoprofenum
  • K 4277
Definition
A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-(1-oxo-1,3-dihydroisoindol-2-yl)phenyl group. Initially used as an anti-inflammatory and analgesic, it was withdrawn from the market due to causing severe gastrointestinal bleeding. It has been subsequently found to increase production of the survival motor neuron protein.
References
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
is a type of
has_functional_parent
has_role
Phenotype
Phenotype resulting from indoprofen
Phenotype where environments contain indoprofen
Phenotype modified by environments containing indoprofen
Human Disease Model
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