dolutegravir

Term ID

CHEBI:76010

Synonyms

(4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
S/GSK1349572

Definition

A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (4R,12aS)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic acid with the amino group of 2,4-difluorobenzylamine. Used (as its sodium salt) for treatment of HIV-1.

References

(all 33)

Ontology

ChEBI ( EBI )

Relationships

is a type of: difluorobenzene monocarboxylic acid amide organic heterotricyclic compound secondary carboxamide

difluorobenzene monocarboxylic acid amide organic heterotricyclic compound secondary carboxamide Show first 5 Terms
has_role: HIV-1 integrase inhibitor

HIV-1 integrase inhibitor Show first 5 Terms
inverse is_conjugate_base_of: dolutegravir(1-)

dolutegravir(1-) Show first 5 Terms
is_conjugate_acid_of: dolutegravir(1-)

dolutegravir(1-) Show first 5 Terms

Phenotype

Phenotype resulting from dolutegravir

Phenotype where environments contain dolutegravir

Phenotype modified by environments containing dolutegravir

Human Disease Model